Ok guys, but if CIC has the information saying that for PR only Express Entry can do Upfront, why people insist and going against the official instructions and make your file more complicate. Just follow the instructions, we already got the most awful document: CSQ, now it's the easiest and relaxing part.....
See the official instructions here:
Instructions
Information on medical instructions
will be provided to you by the IRCC office
. When you receive your assessment notice you will also receive medical forms for yourself (and any dependants,
if applicable) and instructions on how to access a list of doctors in your area who are authorized to conduct immigration medical examinations (see below). You are not required to have a medical examination before you submit your application forms.
https://www.canada.ca/en/immigration-refugees-citizenship/services/application/application-forms-guides/guide-q7000-application-permanent-residence-quebec-skilled-worker-class.html#EQ73