As of December 1, 2011, if you are applying under the Provincial Nominee Program, you must submit your application to the Centralized Intake Office (CIO) in Sydney, Nova Scotia. Once you have gathered all required forms and documents listed in the Document Checklist, send your application to:
Citizenship and Immigration
Provincial Nominee Program
Centralized Intake Office
PO Box 1450
Sydney, Nova Scotia
B1P 6K5
Canada
If the CIO determines that your application is complete, it will be sent to the appropriate CIC processing office for processing. The processing office will contact you for further documentation once they are ready to process your application.
If your application does not include all of the documents and forms set out in the checklist, CIC will return it to you. Do not provide documents which are not listed in the checklist.
Note: Applications that were sent prior to December 1, 2011 and that are received on or after this date at the visa office will be processed by the office as long they are complete.
http://www.cic.gc.ca/english/immigrate/provincial/apply-application.asp