Everyone's situation is different. It's not one size fits all. If people did not meet MEC when they received an ITA, they will be refused. No questions asked. However, if they met MEC and got an ITA but they can complete their experience before their e-APR, they will be fine.
To give you a clear example, let's say candidate A and B get an ITA in the last week draw and both these candidates received it early by a few weeks. Candidate A is a CEC candidate who claimed 2 years of Canadian work experience which he/she will complete a few days after the ITA while Candidate B is a CEC candidate who claimed a year of Canadian work experience but did not have it on or before the ITA date, Now, Candidate A can wait until they have two years of experience and apply after that, their score at ITA and e-APR will match when
the VO manually calculates it. Thus, it won't be refused. Candidate B on the other hand may have their application refused due to not meeting MEC at the time of ITA. In short, one must MEC at ITA and e-APR while your CRS score should be satisfied at the time of e-APR. If for whatever reasons, Candidate A submits their application before they have two years of work experience, they won't get credit for that and without that credit, if their score falls below the cut-off, it will be refused.
So, please don't misguide people here. I have cited several sections under A11.2 in this post:
https://www.canadavisa.com/canada-immigration-discussion-board/threads/to-accept-ita-or-to-decline-based-on-calculation-of-work-experience.687189/post-8614249. Take a look,