Age is exempted when it drops below, so dont worry about CRS drop after NOI is issued..
below are the items you have notify if any changes after submitting application (
http://www.mri.gov.on.ca/repository/oinp_en_hcp.pdf, p27)
Changes in Personal Information
The OINP must be notified if there are any changes to the information provided in
your application, including (but not limited to):
Change in contact information
Change in immigration status (expiration or change in temporary workpermit)
Change in family composition due to:
Marriage or common-law relationship
Birth of a child
Change of custody of a child
Divorce/separation
Death