If you are an out of province graduate you need to work for at least a year in Manitoba before you can apply for MPNP . If you didn't school in Canada at all, this may not apply to you, this rule is only for international students, there are other path ways for PNP for international skilled workers...
You can check the website for info- http://www.gov.mb.ca/ie/study/immigrat.html
You can check the website for info- http://www.gov.mb.ca/ie/study/immigrat.html