Can I go on vacation while my application for permanent residence is being processed?
Starting November 30, 2014, caregivers will have access to two new pathways to permanent residence. Read more about the improvements to the Caregiver Program.
Taking a vacation outside of Canada should not affect your application for permanent residence. However, if you leave Canada while your application is being processed, you may not be allowed to come back into Canada. Each time you come back, you must meet all the rules for entering the country.
If you leave Canada and want to return, you must have:
a valid passport or other travel documents;
a valid work permit, if you are returning to work in Canada; and
a valid temporary resident visa, if you are a citizen of a country for which Canada requires one.
ALSO THIS:
•If you have a single-entry visa this allows you to enter Canada once. If you leave Canada during your authorized stay, you must get a new visitor visa to re-enter Canada, unless you visit the United States or St. Pierre and Miquelon. If you visit those places, you can return to Canada without a new visa, as long as you: ◦return within the period that the Canadian immigration officer initially authorized when you first entered Canada (on your visa, it is either a handwritten date or 6 months from the date of the entry stamp); or
◦have a valid visitor record, work permit, study permit or temporary resident permit (authorizing re-entry), and return within the period that the officer initially authorized
Found this under the CIC Help Desk answers