1. No need to retest as per my understanding
Check this link, it says so
https://www.canada.ca/en/immigration-refugees-citizenship/services/immigrate-canada/express-entry/become-candidate/invitations-apply.html
2. Better to be safe than sorry. I would reissue it, if I were you. Also, if this will impact your points (selection factors grid), then definitely you need to reissue.
3. You need a new PoF for 6 months before e-APR. I don't think you need to attach the earlier statement in that case, as the new one is more up to date and contains the required amount.
4. No need. MOJ translation is fine. It says that you have no criminal verdicts, right?
5. I don't know how is your medical condition, but quitting smoking in general is good for you, so now would be a good time
Just kidding, I don't think it should impact the test. Research what they check for.
Good luck.