That is really unfortunate and I am sorry to hear about that. Apparently I think a few members on this forum got rejected at the ADR, for pretty much the same reason as you, they wanted to hear their spouses' story. Yes MC or IRB will never lay a finger on VO mistake, because VO doesn't bear the responsibility to have a legitimate reason to reject your sponsorship, it is all about preception. If the MC and ERO are satisfied about your story, most likely your wife just need to match up with your story at the full hearing in order to pass the appeal. However if you try to submit a new sponsorship, I heard unless you have some substantial evidence which is different from before (for example the birth of a child), otherwise most likely the VO will just reject you for the same reason. Maybe other members on this forum can shed some light on how you can proceed regarding a full hearing or a new submission.