I printed all of mine out on printer paper (high quality) and wrote the names and places everywhere, date is applicable. They asked in my appl when the wedding was, so they can do the math.
I only submitted 11 pictures, though, so it was easy.
If they are digital, you could combine several on to one page with a heading "Wedding, X date" and list people as needed.
I would only really bother to list important people; family and friends who you listed in the application as having met your spouse.
Just my opinion, but 250 is excessive. Photos aren't the end all, be all of proofs.