The rules are made in such a way to be flexible for the one who evaluates the file
And it's bad for us since they can play tricks with applicants based on that. Formally, AOT is assigned based on the diploma/training irrespective of the fact that somebody worked not in the field. Apart of that, the minimum work experience that an applicant must possess is 6 months and it can be in any occupation listed in the NOC. Thus, if your friend has a nursing degree that's 16 points, and if she has 6+ months of experience in any NOC occupation she qualifies. Of course each application is on a case by case basis and an explanation might be required during interview for the reason why she didn't work in the field. But, considering only eligibility factors there shouldn't be any problem.
