I don't think you need to reply to anyone.
you may follow the steps to continue.
ontarioimmigration.ca/en/pnp/OI_PNP_EE_CAPITAL_HOW.html
Step 3: Apply to OINP under the Human Capital Priorities Stream
To apply, you must submit your application through the OINP e-Filing Portal and ensure that you include all the required supporting documents.
All applicants must indicate which federal immigration program they wish to be assessed against: the Federal Skilled Worker Program (FSWP) or the Canadian Experience Class (CEC).
The application fee is $1,500. The fee covers the cost of processing your application and is non-refundable once you submit your application. Your fee must be paid online by credit card only (VISA or MasterCard) before your application can be submitted.
OINP will assess your nomination according to the Human Capital Priorities Stream eligibility criteria. Your application will also be assessed to ensure you meet the FSWP or CEC criteria.
Step 4: Accept nomination from Ontario and apply for permanent residence
If your application is approved by Ontario, you will receive a letter from OINP through your IRCC online account notifying you of your nomination. You have 30 calendar days to accept the nomination from Ontario in the Express Entry system.
A nomination from Ontario will give you an additional 600 points in the Comprehensive Ranking System (CRS) and you will receive an invitation to apply for permanent residence from IRCC.
Once you receive an invitation to apply from IRCC, you have 90 calendar days to submit your application for permanent residence to IRCC.