Hi, sorry to hear that and I hope my reply doesn't offend or hurt you. I say accept your ITA rather than rejecting it as the process looks very laborious and time consuming one. Now, i'm sure she can be taken on a wheel chair post surgery. As a part of medical exams , you need to be taking routine urine analysis, serum analysis (including HIV & other STDs), Chest X-ray (for TB), Hypertension, diabetes, kidney related and other autoimmune disorders and any other worth findings from the panel of doctors. So, all these should go well for your spouse except that she cant walk for a while. As these are one time test and the results are valid for 12 months. fractures of your wife shouldn't really affect her medicals and I'm sure doctors would recommend the same. By the time she is normal, you will have a PR.