Tim Horton's Franchise information:
http://www.timhortons.com/ca/en/join/franchise_ca_program.html
Basically about $200k cash up front, the remaining 250-300k can be financed through loans.
Tim Hortons does take a franchise fee of 15% of your profits though, which is quite a lot. Most franchises only take about 5-8%, and the big fast food names take about 10%. But they do everything for you including acquiring the location, training the staff, hiring a manager, etc.
You have to go through a selection process to qualify for a franchise - they pick you, you don't pick them. I heard that the initial investment can be recouped within 1-2 years, and most people sell off their franchise after the license expires in 10 years for a tidy profit. You NEVER see an empty Tim Horton's, regardless of the time of day or weather, so you know it's a good investment.
For information about other franchises, you can check it out here: http://www.cfa.ca/MemberCategories.aspx - it is not a finite list as there are many companies not registered with them.
I am looking to start a franchise myself in the next 5-10 years, after establishing a strong line of credit to qualify for a loan that big. So if you're interested in a partner you know where to look. I have been researching all the different brand names and asking around about profit margins for about 2 years now. Of course Tim Horton's would be the best but there is a possibility that they won't select you and there could be a long waiting period just to score the initial interview.