IF you already have your PR why does it matter your CRS score? you are already a permanent resident and as such should not matter anymore, you can request a PR for your wife without the CRS score as a spouse of a permanent resident.
now for other regular folks that have not yet recieved the eCORP or the PR confirmation, married while in th eprocess of PR is a change of personal status, as such this change should be notified to IRCC and update your profile to include this change plus your spouse details, in this case i would suggest to speak with a profesional cause your CRS score would be greatly impacted with a spouse (reduced), if your applying using only your personal information, however in some cases having a partner would increase the point as a couple. you might be abe to check more details here.
https://www.cicnews.com/2021/05/express-entry-couples-and-the-comprehensive-ranking-system-0518059.html#gs.5x38tx