Thanks @legalfalconThere is no bar as such. You can create multiple profile, with you as the PA and not the one as your spouse as PA. Technically they re different profiles.
Also, once you submit an application, the profile is no longer in the pool, so there is nothing stopping you from creating another profile. What IRCC does not want you doing is creating multiple profiles with the same details. You can do it, but not recommended and not ideal either.
@Vikram_kumar123 : Then you can create another profile and wait for current submitted application status. If you get ITA, any way you will have 90 days to submit, until that time you can check eligibility status and take decision.