@KuriousMind
Did you clim points for your job, if you did, then you should wait until you receive your COPR.
If you claimed points for arranged employment, one of the conditions was that the offer would be "for at least one year after [IRCC] issue(s) your permanent resident visa." If you leave your job, then the "year after clause will also go away" as the employer who gave you that undertaking will withdraw the offer, and thus you will lose the points.
So far IRCC has not issued any circulars or policy in this regard. As soon as your change your job, and if your application is still in progress, you have to inform IRCC, and your offer of arranged employment will be subject to verification, even if your eligibility is passed.