Whether or not a TRV is required (in addition to the Study Permit) is dependent on your citizenship and/or country residence. As you have never specified your nationality (nor your spouse's), I listed all possible fees you might be hit with. If you are a citizen of a visa-exempt nation, then you need only a study permit. If you are not visa exempt, you don't have to apply for a TRV separately from the study permit ... both can be accomplished on the same application. One correction from my earlier post: if you fall into this category (i.e., need both a TRV and a study poermit) you do NOT need to pay the fees for both. The $125 application fee covers both. If you want your spouse to come with you to Canada while you attend school, she can be added to your application. If she travels separately from you and joins you in Canada at a later date, then she must file for a TRV separately (on her own application) and pay the TRV application fee, unless she's from a visa-exempt nation. In either case, if you want an open work permit for your spouse, you/she will need to pay the fee for the work permit as well.
A few other related points that may or may not apply to your specific situation:
1. If you're not a citizen of the country from which you apply for a study permit, then you MUST have current and legal status within that country at the time you request a study permit.
2. You can't get a study permit (or even sumit an application for one) until you have applied to and been accepted by a school in Canada. Once you've been accepted and have paid for the first term, the school will issue you an acceptance letter that details the program of study, start date of the program, duration of the program, and the fact that you've paid for the first term tuition. Without this letter in hand, you CANNOT obtain a study permit.
Best of luck!