Yes, you can apply without the LMO but mention the LMO reference number and when it was applied. CIC generally holds the application for 2 months before processing it, and hopefully you get the confirmation by then. When you do, call the CIC call centre and tell them and they will pass this information to the visa office/processing centre.
Be sure to apply for extension before your work permit expires so as to have implied status(for same employer). Note that if your application is denied, you still have 90 days to restore status provided you have your LMO confirmation.
garry_luarca said:
I received my LMO reference number but i dont have my lmo confirmation letter, can i apply for work permit even without it? please help