I am not sure about that but it is look like you are changing your career from commerce to science. If you have good explanation on that in your SOP, I think that will be OK....wait for some other expert response.
I have done HSC in commerce.
Than went for BSCIT due to good score in IT and maths .And now i want to do mba but cannot do it because of 15 years education and they require 16 years of education thats y choice business mgt course